Embeddings from deep learning transfer GO annotations beyond homology

Abstract Knowing protein function is crucial to advance molecular and medical biology, yet experimental function annotations through the Gene Ontology (GO) exist for fewer than 0.5% of all known proteins. Computational methods bridge this sequence-annotation gap typically through homology-based anno...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Maria Littmann, Michael Heinzinger, Christian Dallago, Tobias Olenyi, Burkhard Rost
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/30047864d85f4054b8b99879adff217c
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!