Viral Diversity Threshold for Adaptive Immunity in Prokaryotes

ABSTRACT Bacteria and archaea face continual onslaughts of rapidly diversifying viruses and plasmids. Many prokaryotes maintain adaptive immune systems known as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (Cas). CRISPR-Cas systems are genomic sensor...

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Autores principales: Ariel D. Weinberger, Yuri I. Wolf, Alexander E. Lobkovsky, Michael S. Gilmore, Eugene V. Koonin
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://doaj.org/article/356baaaeaa3f49c2814b91ecfb4b9ab5
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