Full design automation of multi-state RNA devices to program gene expression using energy-based optimization.
Small RNAs (sRNAs) can operate as regulatory agents to control protein expression by interaction with the 5' untranslated region of the mRNA. We have developed a physicochemical framework, relying on base pair interaction energies, to design multi-state sRNA devices by solving an optimization p...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2013
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/36ff29ef71b04a09b075c750b2a94d3a |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|