High-Throughput Screening Identifies Genes Required for <italic toggle="yes">Candida albicans</italic> Induction of Macrophage Pyroptosis

ABSTRACT The innate immune system is the first line of defense against invasive fungal infections. As a consequence, many successful fungal pathogens have evolved elegant strategies to interact with host immune cells. For example, Candida albicans undergoes a morphogenetic switch coupled to cell wal...

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Auteurs principaux:	Teresa R. O’Meara, Kwamaa Duah, Cynthia X. Guo, Michelle E. Maxson, Ryan G. Gaudet, Kristy Koselny, Melanie Wellington, Michael E. Powers, Jessie MacAlpine, Matthew J. O’Meara, Amanda O. Veri, Sergio Grinstein, Suzanne M. Noble, Damian Krysan, Scott D. Gray-Owen, Leah E. Cowen
Format:	article
Langue:	EN
Publié:	American Society for Microbiology 2018
Sujets:	Candida cell wall remodelling functional genomics fungal morphogenesis fungal pathogenesis host-pathogen interaction Microbiology QR1-502
Accès en ligne:	https://doaj.org/article/37c1c8c11e4b4ed3843ff6f59b92ef9d
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High-Throughput Screening Identifies Genes Required for <italic toggle="yes">Candida albicans</italic> Induction of Macrophage Pyroptosis

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