Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum.

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum.

Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) molecules displayed on the erythrocyte surface...

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Bibliographic Details
Main Authors: Christopher J Tonkin, Céline K Carret, Manoj T Duraisingh, Till S Voss, Stuart A Ralph, Mirja Hommel, Michael F Duffy, Liliana Mancio da Silva, Artur Scherf, Alasdair Ivens, Terence P Speed, James G Beeson, Alan F Cowman
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/39d35c51578e4af19b3a93002aacacda
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https://doaj.org/article/39d35c51578e4af19b3a93002aacacda

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