Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex

Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex

A variety of biological differences exist between strains and phylogenetic lineages in the Mycobacterium tuberculosis complex (MTBC). Here, the authors perform RNAseq and methylome analysis of the main clades of the MTBC and show variation in transcriptional profiles is mainly due to mutations in tr...

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Autores principales: Álvaro Chiner-Oms, Michael Berney, Christine Boinett, Fernando González-Candelas, Douglas B. Young, Sebastien Gagneux, William R. Jacobs, Julian Parkhill, Teresa Cortes, Iñaki Comas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/420da98a568148859292e03efed69a7b
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