Anti-metastatic effect of GV1001 on prostate cancer cells; roles of GnRHR-mediated Gαs-cAMP pathway and AR-YAP1 axis
Abstract Background Gonadotropin-releasing hormone receptor (GnRHR) transmits its signal via two major Gα-proteins, primarily Gαq and Gαi. However, the precise mechanism underlying the functions of Gαs signal in prostate cancer cells is still unclear. We have previously identified that GV1001, a fra...
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Auteurs principaux: | , , , , , |
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Format: | article |
Langue: | EN |
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BMC
2021
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Accès en ligne: | https://doaj.org/article/4211061cf8bf472e97ea786f0322647f |
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