Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone
Abstract Persistent ER stress, mitochondrial dysfunction and failure of the heat shock response (HSR) are fundamental hallmarks of insulin resistance (IR); one of the early core metabolic aberrations that leads to type 2 diabetes (T2D). The antioxidant α-lipoic acid (ALA) has been shown to attenuate...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
|
| Subjects: | |
| Online Access: | https://doaj.org/article/465554f1f2074a2bbf23553f639d9bf4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|