Multisystem Analysis of <italic toggle="yes">Mycobacterium tuberculosis</italic> Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface

Multisystem Analysis of <italic toggle="yes">Mycobacterium tuberculosis</italic> Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface

ABSTRACT Tuberculosis is the leading killer among infectious diseases worldwide. Increasing multidrug resistance has prompted new approaches for tuberculosis drug development, including targeted inhibition of virulence determinants and of signaling cascades that control many downstream pathways. We...

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Auteurs principaux: Xavier Carette, John Platig, David C. Young, Michaela Helmel, Albert T. Young, Zhe Wang, Lakshmi-Prasad Potluri, Cameron Stuver Moody, Jumei Zeng, Sladjana Prisic, Joseph N. Paulson, Jan Muntel, Ashoka V. R. Madduri, Jorge Velarde, Jacob A. Mayfield, Christopher Locher, Tiansheng Wang, John Quackenbush, Kyu Y. Rhee, D. Branch Moody, Hanno Steen, Robert N. Husson
Format: article
Langue:EN
Publié: American Society for Microbiology 2018
Sujets:
Mycobacterium tuberculosis
PknB
Ser/Thr protein kinase
signal transduction
two-component regulatory systems
Microbiology
QR1-502
Accès en ligne:https://doaj.org/article/499cf436426a467c922809513e71e00a
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https://doaj.org/article/499cf436426a467c922809513e71e00a

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