Predictability of evolutionary trajectories in fitness landscapes.
Experimental studies on enzyme evolution show that only a small fraction of all possible mutation trajectories are accessible to evolution. However, these experiments deal with individual enzymes and explore a tiny part of the fitness landscape. We report an exhaustive analysis of fitness landscapes...
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Autores principales: | Alexander E Lobkovsky, Yuri I Wolf, Eugene V Koonin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/4a480d0839954830b8e1433829248b14 |
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