Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

Abstract The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-CoV-2 differential gene expression signatures derived from publicly available data. We utilized three independent published studies to acquire...

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Autores principales: Brian L. Le, Gaia Andreoletti, Tomiko Oskotsky, Albert Vallejo-Gracia, Romel Rosales, Katharine Yu, Idit Kosti, Kristoffer E. Leon, Daniel G. Bunis, Christine Li, G. Renuka Kumar, Kris M. White, Adolfo García-Sastre, Melanie Ott, Marina Sirota
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4c2062c1199f494bb0611974876e19c4
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https://doaj.org/article/4c2062c1199f494bb0611974876e19c4

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