Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
Abstract The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-CoV-2 differential gene expression signatures derived from publicly available data. We utilized three independent published studies to acquire...
Guardado en:
Autores principales: | Brian L. Le, Gaia Andreoletti, Tomiko Oskotsky, Albert Vallejo-Gracia, Romel Rosales, Katharine Yu, Idit Kosti, Kristoffer E. Leon, Daniel G. Bunis, Christine Li, G. Renuka Kumar, Kris M. White, Adolfo García-Sastre, Melanie Ott, Marina Sirota |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4c2062c1199f494bb0611974876e19c4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Niacin as a drug repositioning candidate for hyperphosphatemia management in dialysis patients
por: Shin S, et al.
Publicado: (2014) -
Repositioning the Role of Written Sources in Archaeological Research
por: Zorica Kuzmanović
Publicado: (2016) -
GS&E journal > Repositioning Messeturm – Maximum Transparency
por: Steffen Feirabend, et al.
Publicado: (2020) -
Drug Repositioning For Allosteric Modulation of VIP and PACAP Receptors
por: Ingrid Langer, et al.
Publicado: (2021) -
Resheathing and Repositioning During Transcatheter Aortic Valve Implantation
por: Rodrigo Bagur
Publicado: (2021)