Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements
Glucocorticoid receptor (GR) regulates immunity and inflammation but the mechanisms by which GR represses proinflammatory genes are still being debated. Here the authors use a multidisciplinary approach and show that GR binds to a cryptic site within genome-wide NFκB DNA response elements to repress...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/4e26ab6d87a84291886bf3c3f88bfcfb |
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