The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from <named-content content-type="genus-species">Staphylococcus aureus</named-content>

ABSTRACT The innate immune system uses Toll-like receptor (TLR) 2 to detect conserved bacterial lipoproteins of invading pathogens. The lipid anchor attaches lipoproteins to the cytoplasmic membrane and prevents their release from the bacterial cell envelope. How bacteria release lipoproteins and ho...

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Auteurs principaux: Katja Schlatterer, Christian Beck, Dennis Hanzelmann, Marco Lebtig, Birgit Fehrenbacher, Martin Schaller, Patrick Ebner, Mulugeta Nega, Michael Otto, Dorothee Kretschmer, Andreas Peschel
Format: article
Langue:EN
Publié: American Society for Microbiology 2018
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Accès en ligne:https://doaj.org/article/50db06f6b2f1472d8fdc42ff1add844b
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