Thorough investigation of a canine autoinflammatory disease (AID) confirms one main risk locus and suggests a modifier locus for amyloidosis.

Thorough investigation of a canine autoinflammatory disease (AID) confirms one main risk locus and suggests a modifier locus for amyloidosis.

Autoinflammatory disease (AID) manifests from the dysregulation of the innate immune system and is characterised by systemic and persistent inflammation. Clinical heterogeneity leads to patients presenting with one or a spectrum of phenotypic signs, leading to difficult diagnoses in the absence of a...

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Main Authors: Mia Olsson, Linda Tintle, Marcin Kierczak, Michele Perloski, Noriko Tonomura, Andrew Lundquist, Eva Murén, Max Fels, Katarina Tengvall, Gerli Pielberg, Caroline Dufaure de Citres, Laetitia Dorso, Jérôme Abadie, Jeanette Hanson, Anne Thomas, Peter Leegwater, Åke Hedhammar, Kerstin Lindblad-Toh, Jennifer R S Meadows
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/55baf306337e4da0b85824b50133aec7
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