De novo [PSI +] prion formation involves multiple pathways to form infectious oligomers
Abstract Prion and other neurodegenerative diseases are associated with misfolded protein assemblies called amyloid. Research has begun to uncover common mechanisms underlying transmission of amyloids, yet how amyloids form in vivo is still unclear. Here, we take advantage of the yeast prion, [PSI +...
Enregistré dans:
Auteurs principaux: | Jaya Sharma, Brett T. Wisniewski, Emily Paulson, Joanna O. Obaoye, Stephen J. Merrill, Anita L. Manogaran |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/5a38227647ac4f6fa2ac72c486fdc23c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The [PSI +] yeast prion does not wildly affect proteome composition whereas selective pressure exerted on [PSI +] cells can promote aneuploidy
par: Patrick H. W. Chan, et autres
Publié: (2017) -
PrP(Sc)-specific antibodies with the ability to immunodetect prion oligomers.
par: Mourad Tayebi, et autres
Publié: (2011) -
Magnetic microparticle-based multimer detection system for the detection of prion oligomers in sheep
par: Lim K, et autres
Publié: (2015) -
Assessment of inactivating stop codon mutations in forty Saccharomyces cerevisiae strains: implications for [PSI] prion- mediated phenotypes.
par: David A Fitzpatrick, et autres
Publié: (2011) -
Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells
par: Hideyuki Hara, et autres
Publié: (2021)