Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b

Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b

In the germinal center (GC), B and T cells interact to induce the production of protective antibodies against threats. Here the authors show that microRNA miR-146a modulates CD40 signaling in GC B cells, while both miR-146a and miR-146b synergize to control GC T cell responses, thereby implicating i...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sunglim Cho, Hyang-Mi Lee, I-Shing Yu, Youn Soo Choi, Hsi-Yuan Huang, Somaye Sadat Hashemifar, Ling-Li Lin, Mei-Chi Chen, Nikita D. Afanasiev, Aly Azeem Khan, Shu-Wha Lin, Alexander Y. Rudensky, Shane Crotty, Li-Fan Lu
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/5b06837f8ef2466591810930fcb8fa03
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/5b06837f8ef2466591810930fcb8fa03

Documents similaires