Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

The development of native-like envelope trimers has been a major focus in the efforts to produce HIV vaccines. Here the authors demonstrate the production and characterization of virus-like nanoparticles displaying trimeric HIV-1 antigens with the potential to elicit broadly neutralizing antibodies.

Saved in:
Bibliographic Details
Main Authors: Linling He, Natalia de Val, Charles D. Morris, Nemil Vora, Therese C. Thinnes, Leopold Kong, Parisa Azadnia, Devin Sok, Bin Zhou, Dennis R. Burton, Ian A Wilson, David Nemazee, Andrew B. Ward, Jiang Zhu
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/6312ec547362425ea3f5f742d4a2358e
Tags: Add Tag
No Tags, Be the first to tag this record!