Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

The development of native-like envelope trimers has been a major focus in the efforts to produce HIV vaccines. Here the authors demonstrate the production and characterization of virus-like nanoparticles displaying trimeric HIV-1 antigens with the potential to elicit broadly neutralizing antibodies.

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Autores principales:	Linling He, Natalia de Val, Charles D. Morris, Nemil Vora, Therese C. Thinnes, Leopold Kong, Parisa Azadnia, Devin Sok, Bin Zhou, Dennis R. Burton, Ian A Wilson, David Nemazee, Andrew B. Ward, Jiang Zhu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6312ec547362425ea3f5f742d4a2358e
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spelling	oai:doaj.org-article:6312ec547362425ea3f5f742d4a2358e2021-12-02T14:40:11ZPresenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles10.1038/ncomms120412041-1723https://doaj.org/article/6312ec547362425ea3f5f742d4a2358e2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms12041https://doaj.org/toc/2041-1723The development of native-like envelope trimers has been a major focus in the efforts to produce HIV vaccines. Here the authors demonstrate the production and characterization of virus-like nanoparticles displaying trimeric HIV-1 antigens with the potential to elicit broadly neutralizing antibodies.Linling HeNatalia de ValCharles D. MorrisNemil VoraTherese C. ThinnesLeopold KongParisa AzadniaDevin SokBin ZhouDennis R. BurtonIan A WilsonDavid NemazeeAndrew B. WardJiang ZhuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Linling He Natalia de Val Charles D. Morris Nemil Vora Therese C. Thinnes Leopold Kong Parisa Azadnia Devin Sok Bin Zhou Dennis R. Burton Ian A Wilson David Nemazee Andrew B. Ward Jiang Zhu Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles
description	The development of native-like envelope trimers has been a major focus in the efforts to produce HIV vaccines. Here the authors demonstrate the production and characterization of virus-like nanoparticles displaying trimeric HIV-1 antigens with the potential to elicit broadly neutralizing antibodies.
format	article
author	Linling He Natalia de Val Charles D. Morris Nemil Vora Therese C. Thinnes Leopold Kong Parisa Azadnia Devin Sok Bin Zhou Dennis R. Burton Ian A Wilson David Nemazee Andrew B. Ward Jiang Zhu
author_facet	Linling He Natalia de Val Charles D. Morris Nemil Vora Therese C. Thinnes Leopold Kong Parisa Azadnia Devin Sok Bin Zhou Dennis R. Burton Ian A Wilson David Nemazee Andrew B. Ward Jiang Zhu
author_sort	Linling He
title	Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles
title_short	Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles
title_full	Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles
title_fullStr	Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles
title_full_unstemmed	Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles
title_sort	presenting native-like trimeric hiv-1 antigens with self-assembling nanoparticles
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/6312ec547362425ea3f5f742d4a2358e
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Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

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