Siglec-7 May Limit Natural Killer Cell–mediated Antitumor responses in Bladder Cancer Patients

Siglec-7 May Limit Natural Killer Cell–mediated Antitumor responses in Bladder Cancer Patients

Aberrant glycosylation actively contributes to tumor progression and is a key hallmark of cancer. Most of the glycan moieties expressed on the surface of cancer cells are sialic acids that may modulate antitumor immune responses via binding to sialic acid–binding immunoglobulin-like lectins (Siglecs...

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Bibliographic Details
Main Authors: Sulayman Benmerzoug, Mathieu F. Chevalier, Laura Villier, Sylvain Nguyen, Valérie Cesson, Anna K. Schneider, Florence Dartiguenave, Sonia-Christina Rodrigues-Dias, Ilaria Lucca, Patrice Jichlinski, Beat Roth, Denise Nardelli-Haefliger, Laurent Derré
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Bladder cancer
Siglec-7
Natural killer cells
Immunoregulation
Immune checkpoint
Diseases of the genitourinary system. Urology
RC870-923
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/66cfbf05dc5a4c1abdec773b93fd4a9e
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