Protective effect of dexmedetomidine in cecal ligation perforation-induced acute lung injury through HMGB1/RAGE pathway regulation and pyroptosis activation
Sepsis remains a major cause of mortality and morbidity in intensive care units. Dexmedetomidine (DEX) has been reported to attenuate cecal ligation perforation (CLP)-stimulated acute lung injury (ALI) by downregulating high-mobility group protein 1 (HMGB1) and receptor for advanced glycation end pr...
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| Auteurs principaux: | , , , , , |
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| Format: | article |
| Langue: | EN |
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Taylor & Francis Group
2021
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| Accès en ligne: | https://doaj.org/article/6ac67c1f8d094b458a6af15a2e0a6b7e |
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