An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

Typhoid fever is caused by Salmonella enterica serovar Typhi (S. Typhi). This study examines ∼2,000 clinical isolates of S. Typhi to show highly structured/geographically restricted genomes except rapidly disseminating H58 subclade, and design a genotyping framework for tracking the disease.

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Autores principales: Vanessa K. Wong, Stephen Baker, Thomas R. Connor, Derek Pickard, Andrew J. Page, Jayshree Dave, Niamh Murphy, Richard Holliman, Armine Sefton, Michael Millar, Zoe A. Dyson, Gordon Dougan, Kathryn E. Holt, International Typhoid Consortium
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Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/6b08da9696454b94a36e37e35632c93f
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spelling oai:doaj.org-article:6b08da9696454b94a36e37e35632c93f2021-12-02T14:39:31ZAn extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid10.1038/ncomms128272041-1723https://doaj.org/article/6b08da9696454b94a36e37e35632c93f2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12827https://doaj.org/toc/2041-1723Typhoid fever is caused by Salmonella enterica serovar Typhi (S. Typhi). This study examines ∼2,000 clinical isolates of S. Typhi to show highly structured/geographically restricted genomes except rapidly disseminating H58 subclade, and design a genotyping framework for tracking the disease.Vanessa K. WongStephen BakerThomas R. ConnorDerek PickardAndrew J. PageJayshree DaveNiamh MurphyRichard HollimanArmine SeftonMichael MillarZoe A. DysonGordon DouganKathryn E. HoltInternational Typhoid ConsortiumNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vanessa K. Wong
Stephen Baker
Thomas R. Connor
Derek Pickard
Andrew J. Page
Jayshree Dave
Niamh Murphy
Richard Holliman
Armine Sefton
Michael Millar
Zoe A. Dyson
Gordon Dougan
Kathryn E. Holt
International Typhoid Consortium
An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid
description Typhoid fever is caused by Salmonella enterica serovar Typhi (S. Typhi). This study examines ∼2,000 clinical isolates of S. Typhi to show highly structured/geographically restricted genomes except rapidly disseminating H58 subclade, and design a genotyping framework for tracking the disease.
format article
author Vanessa K. Wong
Stephen Baker
Thomas R. Connor
Derek Pickard
Andrew J. Page
Jayshree Dave
Niamh Murphy
Richard Holliman
Armine Sefton
Michael Millar
Zoe A. Dyson
Gordon Dougan
Kathryn E. Holt
International Typhoid Consortium
author_facet Vanessa K. Wong
Stephen Baker
Thomas R. Connor
Derek Pickard
Andrew J. Page
Jayshree Dave
Niamh Murphy
Richard Holliman
Armine Sefton
Michael Millar
Zoe A. Dyson
Gordon Dougan
Kathryn E. Holt
International Typhoid Consortium
author_sort Vanessa K. Wong
title An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid
title_short An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid
title_full An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid
title_fullStr An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid
title_full_unstemmed An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid
title_sort extended genotyping framework for salmonella enterica serovar typhi, the cause of human typhoid
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/6b08da9696454b94a36e37e35632c93f
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