T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8

Epitopes formed by fusion of more than one self peptide, such as proinsulin and other β cell proteins, can result in the formation of non-self hybrid peptides that can potentially trigger autoimmune responses. Here the authors show how TRBV5 + T cell receptors are geared towards recognition of HLA-D...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Mai T. Tran, Pouya Faridi, Jia Jia Lim, Yi Tian Ting, Goodluck Onwukwe, Pushpak Bhattacharjee, Claerwen M. Jones, Eleonora Tresoldi, Fergus J. Cameron, Nicole L. La Gruta, Anthony W. Purcell, Stuart I. Mannering, Jamie Rossjohn, Hugh H. Reid
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/6cfc61766a5b4c9d973ece4ad2e9ab57
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/6cfc61766a5b4c9d973ece4ad2e9ab57

Ejemplares similares