Manipulating the sensitivity of signal-induced repression: quantification and consequences of altered brinker gradients.

Traditionally, the analysis of gene regulatory regions suffered from the caveat that it was restricted to artificial contexts (e.g. reporter constructs of limited size). With the advent of the BAC recombineering technique, genomic constructs can now be generated to test regulatory elements in their...

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Autores principales: Lucia Gafner, Sascha Dalessi, Eliane Escher, George Pyrowolakis, Sven Bergmann, Konrad Basler
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/6f6b1781f9094256890dc86a23b538de
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