Manipulating the sensitivity of signal-induced repression: quantification and consequences of altered brinker gradients.

Traditionally, the analysis of gene regulatory regions suffered from the caveat that it was restricted to artificial contexts (e.g. reporter constructs of limited size). With the advent of the BAC recombineering technique, genomic constructs can now be generated to test regulatory elements in their...

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Auteurs principaux: Lucia Gafner, Sascha Dalessi, Eliane Escher, George Pyrowolakis, Sven Bergmann, Konrad Basler
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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R
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Accès en ligne:https://doaj.org/article/6f6b1781f9094256890dc86a23b538de
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