TRBP ensures efficient Dicer processing of precursor microRNA in RNA-crowded environments
The RNA binding protein TRBP is a component of the Dicer complex but its role in microRNA biogenesis remains poorly understood. Here the authors use a crowded RNA environment and single-molecule imaging to show that TRBP acts as a gatekeeper to prevent Dicer engagement with pre miRNA-like substrates...
Saved in:
Main Authors: | , , , , , |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
|
Subjects: | |
Online Access: | https://doaj.org/article/7b1687162fec4a0bb83eed9b2f3f28d3 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|