In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

KRAS-driven lung cancers represent an aggressive form of NSCLC. In this study the authors perform an in vivo functional screening and identify GATAD2B as a driver of tumor growth and metastasis in KRAS-driven lung cancer.

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Autores principales:	Caitlin L. Grzeskowiak, Samrat T. Kundu, Xiulei Mo, Andrei A. Ivanov, Oksana Zagorodna, Hengyu Lu, Richard H. Chapple, Yiu Huen Tsang, Daniela Moreno, Maribel Mosqueda, Karina Eterovic, Jared J. Fradette, Sumreen Ahmad, Fengju Chen, Zechen Chong, Ken Chen, Chad J. Creighton, Haian Fu, Gordon B. Mills, Don L. Gibbons, Kenneth L. Scott
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7d3a32362fb643e9a451c28f602e01e5
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spelling	oai:doaj.org-article:7d3a32362fb643e9a451c28f602e01e52021-12-02T17:33:17ZIn vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer10.1038/s41467-018-04572-32041-1723https://doaj.org/article/7d3a32362fb643e9a451c28f602e01e52018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04572-3https://doaj.org/toc/2041-1723KRAS-driven lung cancers represent an aggressive form of NSCLC. In this study the authors perform an in vivo functional screening and identify GATAD2B as a driver of tumor growth and metastasis in KRAS-driven lung cancer.Caitlin L. GrzeskowiakSamrat T. KunduXiulei MoAndrei A. IvanovOksana ZagorodnaHengyu LuRichard H. ChappleYiu Huen TsangDaniela MorenoMaribel MosquedaKarina EterovicJared J. FradetteSumreen AhmadFengju ChenZechen ChongKen ChenChad J. CreightonHaian FuGordon B. MillsDon L. GibbonsKenneth L. ScottNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Caitlin L. Grzeskowiak Samrat T. Kundu Xiulei Mo Andrei A. Ivanov Oksana Zagorodna Hengyu Lu Richard H. Chapple Yiu Huen Tsang Daniela Moreno Maribel Mosqueda Karina Eterovic Jared J. Fradette Sumreen Ahmad Fengju Chen Zechen Chong Ken Chen Chad J. Creighton Haian Fu Gordon B. Mills Don L. Gibbons Kenneth L. Scott In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer
description	KRAS-driven lung cancers represent an aggressive form of NSCLC. In this study the authors perform an in vivo functional screening and identify GATAD2B as a driver of tumor growth and metastasis in KRAS-driven lung cancer.
format	article
author	Caitlin L. Grzeskowiak Samrat T. Kundu Xiulei Mo Andrei A. Ivanov Oksana Zagorodna Hengyu Lu Richard H. Chapple Yiu Huen Tsang Daniela Moreno Maribel Mosqueda Karina Eterovic Jared J. Fradette Sumreen Ahmad Fengju Chen Zechen Chong Ken Chen Chad J. Creighton Haian Fu Gordon B. Mills Don L. Gibbons Kenneth L. Scott
author_facet	Caitlin L. Grzeskowiak Samrat T. Kundu Xiulei Mo Andrei A. Ivanov Oksana Zagorodna Hengyu Lu Richard H. Chapple Yiu Huen Tsang Daniela Moreno Maribel Mosqueda Karina Eterovic Jared J. Fradette Sumreen Ahmad Fengju Chen Zechen Chong Ken Chen Chad J. Creighton Haian Fu Gordon B. Mills Don L. Gibbons Kenneth L. Scott
author_sort	Caitlin L. Grzeskowiak
title	In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer
title_short	In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer
title_full	In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer
title_fullStr	In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer
title_full_unstemmed	In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer
title_sort	in vivo screening identifies gatad2b as a metastasis driver in kras-driven lung cancer
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7d3a32362fb643e9a451c28f602e01e5
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In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

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