Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes

Abstract Apples are well known to have various benefits for the human body. Procyanidins are a class of polyphenols found in apples that have demonstrated effects on the circulatory system and skeletal organs. Osteoarthritis (OA) is a locomotive syndrome that is histologically characterized by carti...

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Main Authors: Isao Masuda, Masato Koike, Shohei Nakashima, Yu Mizutani, Yusuke Ozawa, Kenji Watanabe, Yoko Sawada, Hiroshi Sugiyama, Atsushi Sugimoto, Hidetoshi Nojiri, Koichi Sashihara, Koutaro Yokote, Takahiko Shimizu
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
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Online Access:https://doaj.org/article/807631a87310403fad916501ca20c8ed
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