Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry.
Influenza A virus (IAV) enters host cells by endocytosis followed by acid-activated penetration from late endosomes (LEs). Using siRNA silencing, we found that histone deacetylase 8 (HDAC8), a cytoplasmic enzyme, efficiently promoted productive entry of IAV into tissue culture cells, whereas HDAC1 s...
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Main Authors: | Yohei Yamauchi, Heithem Boukari, Indranil Banerjee, Ivo F Sbalzarini, Peter Horvath, Ari Helenius |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/80a38b8b1c574a3699c6581885e7aa07 |
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