Distinguishing between exploratory and confirmatory preclinical research will improve translation.
Preclinical researchers confront two overarching agendas related to drug development: selecting interventions amid a vast field of candidates, and producing rigorous evidence of clinical promise for a small number of interventions. We suggest that each challenge is best met by two different, complem...
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Main Authors: | Jonathan Kimmelman, Jeffrey S Mogil, Ulrich Dirnagl |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Subjects: | |
Online Access: | https://doaj.org/article/835d26b2650a48708202d848d2b3fd7d |
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