Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’

Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’

High resolution characterisation of the virus specific T cell response to SARS CoV2 provides further understanding to the immune response to the infection. Here the authors apply a reverse phenotyping approach to interrogate the SARS-CoV-2 T cell compartment at single cell resolution.”

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Autores principales: David S. Fischer, Meshal Ansari, Karolin I. Wagner, Sebastian Jarosch, Yiqi Huang, Christoph H. Mayr, Maximilian Strunz, Niklas J. Lang, Elvira D’Ippolito, Monika Hammel, Laura Mateyka, Simone Weber, Lisa S. Wolff, Klaus Witter, Isis E. Fernandez, Gabriela Leuschner, Katrin Milger, Marion Frankenberger, Lorenz Nowak, Katharina Heinig-Menhard, Ina Koch, Mircea G. Stoleriu, Anne Hilgendorff, Jürgen Behr, Andreas Pichlmair, Benjamin Schubert, Fabian J. Theis, Dirk H. Busch, Herbert B. Schiller, Kilian Schober
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/84508b147f414165a4d89699fa0e872a
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https://doaj.org/article/84508b147f414165a4d89699fa0e872a

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