Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’
High resolution characterisation of the virus specific T cell response to SARS CoV2 provides further understanding to the immune response to the infection. Here the authors apply a reverse phenotyping approach to interrogate the SARS-CoV-2 T cell compartment at single cell resolution.”
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Nature Portfolio
2021
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oai:doaj.org-article:84508b147f414165a4d89699fa0e872a2021-12-02T16:24:57ZSingle-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’10.1038/s41467-021-24730-42041-1723https://doaj.org/article/84508b147f414165a4d89699fa0e872a2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24730-4https://doaj.org/toc/2041-1723High resolution characterisation of the virus specific T cell response to SARS CoV2 provides further understanding to the immune response to the infection. Here the authors apply a reverse phenotyping approach to interrogate the SARS-CoV-2 T cell compartment at single cell resolution.”David S. FischerMeshal AnsariKarolin I. WagnerSebastian JaroschYiqi HuangChristoph H. MayrMaximilian StrunzNiklas J. LangElvira D’IppolitoMonika HammelLaura MateykaSimone WeberLisa S. WolffKlaus WitterIsis E. FernandezGabriela LeuschnerKatrin MilgerMarion FrankenbergerLorenz NowakKatharina Heinig-MenhardIna KochMircea G. StoleriuAnne HilgendorffJürgen BehrAndreas PichlmairBenjamin SchubertFabian J. TheisDirk H. BuschHerbert B. SchillerKilian SchoberNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q David S. Fischer Meshal Ansari Karolin I. Wagner Sebastian Jarosch Yiqi Huang Christoph H. Mayr Maximilian Strunz Niklas J. Lang Elvira D’Ippolito Monika Hammel Laura Mateyka Simone Weber Lisa S. Wolff Klaus Witter Isis E. Fernandez Gabriela Leuschner Katrin Milger Marion Frankenberger Lorenz Nowak Katharina Heinig-Menhard Ina Koch Mircea G. Stoleriu Anne Hilgendorff Jürgen Behr Andreas Pichlmair Benjamin Schubert Fabian J. Theis Dirk H. Busch Herbert B. Schiller Kilian Schober Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ |
| description |
High resolution characterisation of the virus specific T cell response to SARS CoV2 provides further understanding to the immune response to the infection. Here the authors apply a reverse phenotyping approach to interrogate the SARS-CoV-2 T cell compartment at single cell resolution.” |
| format |
article |
| author |
David S. Fischer Meshal Ansari Karolin I. Wagner Sebastian Jarosch Yiqi Huang Christoph H. Mayr Maximilian Strunz Niklas J. Lang Elvira D’Ippolito Monika Hammel Laura Mateyka Simone Weber Lisa S. Wolff Klaus Witter Isis E. Fernandez Gabriela Leuschner Katrin Milger Marion Frankenberger Lorenz Nowak Katharina Heinig-Menhard Ina Koch Mircea G. Stoleriu Anne Hilgendorff Jürgen Behr Andreas Pichlmair Benjamin Schubert Fabian J. Theis Dirk H. Busch Herbert B. Schiller Kilian Schober |
| author_facet |
David S. Fischer Meshal Ansari Karolin I. Wagner Sebastian Jarosch Yiqi Huang Christoph H. Mayr Maximilian Strunz Niklas J. Lang Elvira D’Ippolito Monika Hammel Laura Mateyka Simone Weber Lisa S. Wolff Klaus Witter Isis E. Fernandez Gabriela Leuschner Katrin Milger Marion Frankenberger Lorenz Nowak Katharina Heinig-Menhard Ina Koch Mircea G. Stoleriu Anne Hilgendorff Jürgen Behr Andreas Pichlmair Benjamin Schubert Fabian J. Theis Dirk H. Busch Herbert B. Schiller Kilian Schober |
| author_sort |
David S. Fischer |
| title |
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ |
| title_short |
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ |
| title_full |
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ |
| title_fullStr |
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ |
| title_full_unstemmed |
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ |
| title_sort |
single-cell rna sequencing reveals ex vivo signatures of sars-cov-2-reactive t cells through ‘reverse phenotyping’ |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/84508b147f414165a4d89699fa0e872a |
| work_keys_str_mv |
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