Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA.
Viruses that generate capped RNA lacking 2'O methylation on the first ribose are severely affected by the antiviral activity of Type I interferons. We used proteome-wide affinity purification coupled to mass spectrometry to identify human and mouse proteins specifically binding to capped RNA wi...
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Autores principales: | , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/84761bfef68c48ab8b7cff68a5fa0d6c |
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