Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling

Abstract The cancer genome provides the blueprint for identifying oncogenic mutations driving tumor growth and these mutant proteins and pathways are the targets for precision cancer therapies. However, many oncogenes are capable of reprogramming the landscape of active portion of the genome, common...

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Autores principales: Feng Liu, Paul S. Mischel, Webster K. Cavenee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8741ff04de824f7585fff1793dbafe1b
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