PEP-19 modulates calcium binding to calmodulin by electrostatic steering
The protein PEP-19 increases the rates of calcium binding to calmodulin. Here, the authors report the structure of PEP-19 bound to the C-terminal domain of calmodulin, and are able to propose a mechanism for the observed increased calcium association rate.
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Main Authors: | Xu Wang, John A. Putkey |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Subjects: | |
Online Access: | https://doaj.org/article/87656c6f7cf54997bf12ecd08c72d76c |
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