A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids
CD1 proteins present lipid antigens to T cells via the T cell receptor. Here the authors describe T cell reactivity to human membrane lipid moieties and provide structural data to define a molecular mechanism of promiscuous recognition of self-derived phospholipids.
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Auteurs principaux: | , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Sujets: | |
Accès en ligne: | https://doaj.org/article/8b688ab776554395acd758b05b541c3e |
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