Glucose and NAADP trigger elementary intracellular β-cell Ca2+ signals
Abstract Pancreatic β-cells release insulin upon a rise in blood glucose. The precise mechanisms of stimulus-secretion coupling, and its failure in Diabetes Mellitus Type 2, remain to be elucidated. The consensus model, as well as a class of currently prescribed anti-diabetic drugs, are based around...
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Auteurs principaux: | Paula Maria Heister, Trevor Powell, Antony Galione |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/9045c5c0e3dc4eeb89bc5c8eecf10a5d |
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