Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling
Ribosomes tend to stall during the translation of consecutive proline residues, which can be rescued by the co-translational factor EF-P. Here the authors identify a structural element of tRNAProresponsible for specific recognition by EF-P and stimulation of Pro-Pro peptide bond formation.
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2016
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/90d8b72d78184e6a839f81702aa64ca5 |
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| Résumé: | Ribosomes tend to stall during the translation of consecutive proline residues, which can be rescued by the co-translational factor EF-P. Here the authors identify a structural element of tRNAProresponsible for specific recognition by EF-P and stimulation of Pro-Pro peptide bond formation. |
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