Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling

Ribosomes tend to stall during the translation of consecutive proline residues, which can be rescued by the co-translational factor EF-P. Here the authors identify a structural element of tRNAProresponsible for specific recognition by EF-P and stimulation of Pro-Pro peptide bond formation.

Guardado en:

Detalles Bibliográficos
Autores principales:	Takayuki Katoh, Ingo Wohlgemuth, Masanobu Nagano, Marina V. Rodnina, Hiroaki Suga
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/90d8b72d78184e6a839f81702aa64ca5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:90d8b72d78184e6a839f81702aa64ca5
record_format	dspace
spelling	oai:doaj.org-article:90d8b72d78184e6a839f81702aa64ca52021-12-02T14:38:35ZEssential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling10.1038/ncomms116572041-1723https://doaj.org/article/90d8b72d78184e6a839f81702aa64ca52016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11657https://doaj.org/toc/2041-1723Ribosomes tend to stall during the translation of consecutive proline residues, which can be rescued by the co-translational factor EF-P. Here the authors identify a structural element of tRNAProresponsible for specific recognition by EF-P and stimulation of Pro-Pro peptide bond formation.Takayuki KatohIngo WohlgemuthMasanobu NaganoMarina V. RodninaHiroaki SugaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Takayuki Katoh Ingo Wohlgemuth Masanobu Nagano Marina V. Rodnina Hiroaki Suga Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling
description	Ribosomes tend to stall during the translation of consecutive proline residues, which can be rescued by the co-translational factor EF-P. Here the authors identify a structural element of tRNAProresponsible for specific recognition by EF-P and stimulation of Pro-Pro peptide bond formation.
format	article
author	Takayuki Katoh Ingo Wohlgemuth Masanobu Nagano Marina V. Rodnina Hiroaki Suga
author_facet	Takayuki Katoh Ingo Wohlgemuth Masanobu Nagano Marina V. Rodnina Hiroaki Suga
author_sort	Takayuki Katoh
title	Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling
title_short	Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling
title_full	Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling
title_fullStr	Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling
title_full_unstemmed	Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling
title_sort	essential structural elements in trnapro for ef-p-mediated alleviation of translation stalling
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/90d8b72d78184e6a839f81702aa64ca5
work_keys_str_mv	AT takayukikatoh essentialstructuralelementsintrnaproforefpmediatedalleviationoftranslationstalling AT ingowohlgemuth essentialstructuralelementsintrnaproforefpmediatedalleviationoftranslationstalling AT masanobunagano essentialstructuralelementsintrnaproforefpmediatedalleviationoftranslationstalling AT marinavrodnina essentialstructuralelementsintrnaproforefpmediatedalleviationoftranslationstalling AT hiroakisuga essentialstructuralelementsintrnaproforefpmediatedalleviationoftranslationstalling
_version_	1718390964935983104

Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling

Ejemplares similares