Scaffold-based pan-agonist design for the PPARα, PPARβ and PPARγ receptors.
As important members of nuclear receptor superfamily, Peroxisome proliferator-activated receptors (PPAR) play essential roles in regulating cellular differentiation, development, metabolism, and tumorigenesis of higher organisms. The PPAR receptors have 3 identified subtypes: PPARα, PPARβ and PPARγ,...
Enregistré dans:
Auteurs principaux: | Li-Song Zhang, Shu-Qing Wang, Wei-Ren Xu, Run-Ling Wang, Jing-Fang Wang |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/9250f83d504e40b6929ec9013fde4d17 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Peroxisome proliferator-activated receptor (PPAR) γ and PPARα agonists modulate mitochondrial fusion-fission dynamics: relevance to reactive oxygen species (ROS)-related neurodegenerative disorders?
par: Juan M Zolezzi, et autres
Publié: (2013) -
Molecular determinants of magnolol targeting both RXRα and PPARγ.
par: Haitao Zhang, et autres
Publié: (2011) -
Alteration of PPAR‐GAMMA (PPARG; PPARγ) and PTEN gene expression in acute myeloid leukemia patients and the promising anticancer effects of PPARγ stimulation using pioglitazone on AML cells
par: Shadi Esmaeili, et autres
Publié: (2021) -
Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer
par: Manav Korpal, et autres
Publié: (2017) - PPAR research