Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11.
Vesicular trafficking plays a key role in tuning the activity of Notch signaling. Here, we describe a novel and conserved Rab geranylgeranyltransferase (RabGGT)-α-like subunit that is required for Notch signaling-mediated lateral inhibition and cell fate determination of external sensory organs. Thi...
Saved in:
Main Authors: | Wu-Lin Charng, Shinya Yamamoto, Manish Jaiswal, Vafa Bayat, Bo Xiong, Ke Zhang, Hector Sandoval, Gabriela David, Stephen Gibbs, Hsiang-Chih Lu, Kuchuan Chen, Nikos Giagtzoglou, Hugo J Bellen |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
|
Subjects: | |
Online Access: | https://doaj.org/article/951f0ce1a76b4afb825c7f0b62f3bb46 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells.
by: Bo Xiong, et al.
Published: (2012) -
The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7
by: Evgeniya Trofimenko, et al.
Published: (2021) -
Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1
by: Jiqing Du, et al.
Published: (2021) -
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes
by: Shirley Tremel, et al.
Published: (2021) -
Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-γ-stimulated lung epithelial cells
by: Ying-Da Chen, et al.
Published: (2017)