Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning.
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Main Authors: | Adam C. Frank, Shan Huang, Miou Zhou, Amos Gdalyahu, George Kastellakis, Tawnie K. Silva, Elaine Lu, Ximiao Wen, Panayiota Poirazi, Joshua T. Trachtenberg, Alcino J. Silva |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doaj.org/article/9812b8e6055c436ab27e845c4f6d0c38 |
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