Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome
Maintenance of immune homeostasis involves a synergistic relationship between the host and the microbiome. Canonical interferon (IFN) signaling controls responses to acute microbial infection, through engagement of the STAT1 transcription factor. However, the contribution of tonic levels of IFN to i...
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Auteurs principaux: | Isabelle J Marié, Lara Brambilla, Doua Azzouz, Ze Chen, Gisele V Baracho, Azlann Arnett, Haiyan S Li, Weiguo Liu, Luisa Cimmino, Pratip Chattopadhyay, Gregg Silverman, Stephanie S Watowich, Bernard Khor, David E Levy |
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Format: | article |
Langue: | EN |
Publié: |
eLife Sciences Publications Ltd
2021
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Accès en ligne: | https://doaj.org/article/982a4035ae764dbdbb7abc2f4d9fe2a7 |
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