Evaluation of paired-end sequencing strategies for detection of genome rearrangements in cancer.
Paired-end sequencing is emerging as a key technique for assessing genome rearrangements and structural variation on a genome-wide scale. This technique is particularly useful for detecting copy-neutral rearrangements, such as inversions and translocations, which are common in cancer and can produce...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2008
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Acceso en línea: | https://doaj.org/article/a2f362f5a34b4d5685a84b62578c408b |
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