Evaluation of paired-end sequencing strategies for detection of genome rearrangements in cancer.

Paired-end sequencing is emerging as a key technique for assessing genome rearrangements and structural variation on a genome-wide scale. This technique is particularly useful for detecting copy-neutral rearrangements, such as inversions and translocations, which are common in cancer and can produce...

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Autores principales: Ali Bashir, Stanislav Volik, Colin Collins, Vineet Bafna, Benjamin J Raphael
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/a2f362f5a34b4d5685a84b62578c408b
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