USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth
Abstract Ewing sarcoma is the second most common pediatric bone and soft tissue tumor presenting with an aggressive behavior and prevalence to metastasize. The diagnostic translocation t(22;11)(q24;12) leads to expression of the chimeric oncoprotein EWS-FLI1 which is uniquely expressed in all tumor...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/a3adb4d3106e433a8db0de295f5c3477 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|