Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation

It is known that Purkinje cell PKC-dependent depression is involved in the stabilization of self-motion based hippocampal representation. Here the authors describe decreased stability of hippocampal place cells based on allocentric cues in mice lacking Purkinje cell PP2B-dependent potentiation.

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Main Authors:	Julie Marie Lefort, Jean Vincent, Lucille Tallot, Frédéric Jarlier, Chris Innocentius De Zeeuw, Laure Rondi-Reig, Christelle Rochefort
Format:	article
Language:	EN
Published:	Nature Portfolio 2019
Subjects:	Science Q
Online Access:	https://doaj.org/article/a721c79a49814e708b07b51a199488f5
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id	oai:doaj.org-article:a721c79a49814e708b07b51a199488f5
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spelling	oai:doaj.org-article:a721c79a49814e708b07b51a199488f52021-12-02T14:38:37ZImpaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation10.1038/s41467-019-09958-52041-1723https://doaj.org/article/a721c79a49814e708b07b51a199488f52019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09958-5https://doaj.org/toc/2041-1723It is known that Purkinje cell PKC-dependent depression is involved in the stabilization of self-motion based hippocampal representation. Here the authors describe decreased stability of hippocampal place cells based on allocentric cues in mice lacking Purkinje cell PP2B-dependent potentiation.Julie Marie LefortJean VincentLucille TallotFrédéric JarlierChris Innocentius De ZeeuwLaure Rondi-ReigChristelle RochefortNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julie Marie Lefort Jean Vincent Lucille Tallot Frédéric Jarlier Chris Innocentius De Zeeuw Laure Rondi-Reig Christelle Rochefort Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation
description	It is known that Purkinje cell PKC-dependent depression is involved in the stabilization of self-motion based hippocampal representation. Here the authors describe decreased stability of hippocampal place cells based on allocentric cues in mice lacking Purkinje cell PP2B-dependent potentiation.
format	article
author	Julie Marie Lefort Jean Vincent Lucille Tallot Frédéric Jarlier Chris Innocentius De Zeeuw Laure Rondi-Reig Christelle Rochefort
author_facet	Julie Marie Lefort Jean Vincent Lucille Tallot Frédéric Jarlier Chris Innocentius De Zeeuw Laure Rondi-Reig Christelle Rochefort
author_sort	Julie Marie Lefort
title	Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation
title_short	Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation
title_full	Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation
title_fullStr	Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation
title_full_unstemmed	Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation
title_sort	impaired cerebellar purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a721c79a49814e708b07b51a199488f5
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Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation

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