Comprehensive Essentiality Analysis of the <italic toggle="yes">Mycobacterium tuberculosis</italic> Genome via Saturating Transposon Mutagenesis

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Comprehensive Essentiality Analysis of the <italic toggle="yes">Mycobacterium tuberculosis</italic> Genome via Saturating Transposon Mutagenesis

ABSTRACT For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to find loci that are unable to sustain insertion. To date, these studies have analyzed subsaturated libraries, n...

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Main Authors:	Michael A. DeJesus, Elias R. Gerrick, Weizhen Xu, Sae Woong Park, Jarukit E. Long, Cara C. Boutte, Eric J. Rubin, Dirk Schnappinger, Sabine Ehrt, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger
Format:	article
Language:	EN
Published:	American Society for Microbiology 2017
Subjects:	Microbiology QR1-502
Online Access:	https://doaj.org/article/a77bd7f0cb4b428b9bb78ab3fcebcc71
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