Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

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Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

Human leukocyte antigen (HLA) presents peptides to activate T cells, but many aspects in the T cell receptor (TCR)/HLA interaction remain unclear. Here the authors show, via structural data, that two TCRs differentially recognize the same tumour peptide/HLA complex and induce contrasting conformatio...

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Détails bibliographiques
Auteurs principaux:	Kok Fei Chan, Benjamin S. Gully, Stephanie Gras, Dennis X. Beringer, Lars Kjer-Nielsen, Jonathan Cebon, James McCluskey, Weisan Chen, Jamie Rossjohn
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/a7ed25c4fcb740c1b5d4980f12c82203
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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