Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin–ligand-type complexes
Ribosomes assemble through a process involving about 200 biogenesis factors and series of remodeling steps. Here the authors present the structures of the Rea1-MIDAS domain alone and in complex with its binding partners, shedding light on the process of mechanochemical release of the assembly factor...
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Main Authors: | Yasar Luqman Ahmed, Matthias Thoms, Valentin Mitterer, Irmgard Sinning, Ed Hurt |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Subjects: | |
Online Access: | https://doaj.org/article/abf769c706a747f78941e47a6419e9d2 |
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