Functional annotation of rare gene aberration drivers of pancreatic cancer

Next generation sequencing allows the identification of oncogenic driver genes in pancreatic cancer. Here, in an effort to identify additional causal genes, the authors develop a high throughput in vivoscreen and identify genes that whilst infrequently mutated in pancreatic cancer contribute to tumo...

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Autores principales:	Yiu Huen Tsang, Turgut Dogruluk, Philip M. Tedeschi, Joanna Wardwell-Ozgo, Hengyu Lu, Maribel Espitia, Nikitha Nair, Rosalba Minelli, Zechen Chong, Fengju Chen, Qing Edward Chang, Jennifer B. Dennison, Armel Dogruluk, Min Li, Haoqiang Ying, Joseph R. Bertino, Marie-Claude Gingras, Michael Ittmann, John Kerrigan, Ken Chen, Chad J. Creighton, Karina Eterovic, Gordon B. Mills, Kenneth L. Scott
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ad00a3ec62c944099c564237f8e7c498
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spelling	oai:doaj.org-article:ad00a3ec62c944099c564237f8e7c4982021-12-02T16:50:14ZFunctional annotation of rare gene aberration drivers of pancreatic cancer10.1038/ncomms105002041-1723https://doaj.org/article/ad00a3ec62c944099c564237f8e7c4982016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10500https://doaj.org/toc/2041-1723Next generation sequencing allows the identification of oncogenic driver genes in pancreatic cancer. Here, in an effort to identify additional causal genes, the authors develop a high throughput in vivoscreen and identify genes that whilst infrequently mutated in pancreatic cancer contribute to tumour formation.Yiu Huen TsangTurgut DogrulukPhilip M. TedeschiJoanna Wardwell-OzgoHengyu LuMaribel EspitiaNikitha NairRosalba MinelliZechen ChongFengju ChenQing Edward ChangJennifer B. DennisonArmel DogrulukMin LiHaoqiang YingJoseph R. BertinoMarie-Claude GingrasMichael IttmannJohn KerriganKen ChenChad J. CreightonKarina EterovicGordon B. MillsKenneth L. ScottNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yiu Huen Tsang Turgut Dogruluk Philip M. Tedeschi Joanna Wardwell-Ozgo Hengyu Lu Maribel Espitia Nikitha Nair Rosalba Minelli Zechen Chong Fengju Chen Qing Edward Chang Jennifer B. Dennison Armel Dogruluk Min Li Haoqiang Ying Joseph R. Bertino Marie-Claude Gingras Michael Ittmann John Kerrigan Ken Chen Chad J. Creighton Karina Eterovic Gordon B. Mills Kenneth L. Scott Functional annotation of rare gene aberration drivers of pancreatic cancer
description	Next generation sequencing allows the identification of oncogenic driver genes in pancreatic cancer. Here, in an effort to identify additional causal genes, the authors develop a high throughput in vivoscreen and identify genes that whilst infrequently mutated in pancreatic cancer contribute to tumour formation.
format	article
author	Yiu Huen Tsang Turgut Dogruluk Philip M. Tedeschi Joanna Wardwell-Ozgo Hengyu Lu Maribel Espitia Nikitha Nair Rosalba Minelli Zechen Chong Fengju Chen Qing Edward Chang Jennifer B. Dennison Armel Dogruluk Min Li Haoqiang Ying Joseph R. Bertino Marie-Claude Gingras Michael Ittmann John Kerrigan Ken Chen Chad J. Creighton Karina Eterovic Gordon B. Mills Kenneth L. Scott
author_facet	Yiu Huen Tsang Turgut Dogruluk Philip M. Tedeschi Joanna Wardwell-Ozgo Hengyu Lu Maribel Espitia Nikitha Nair Rosalba Minelli Zechen Chong Fengju Chen Qing Edward Chang Jennifer B. Dennison Armel Dogruluk Min Li Haoqiang Ying Joseph R. Bertino Marie-Claude Gingras Michael Ittmann John Kerrigan Ken Chen Chad J. Creighton Karina Eterovic Gordon B. Mills Kenneth L. Scott
author_sort	Yiu Huen Tsang
title	Functional annotation of rare gene aberration drivers of pancreatic cancer
title_short	Functional annotation of rare gene aberration drivers of pancreatic cancer
title_full	Functional annotation of rare gene aberration drivers of pancreatic cancer
title_fullStr	Functional annotation of rare gene aberration drivers of pancreatic cancer
title_full_unstemmed	Functional annotation of rare gene aberration drivers of pancreatic cancer
title_sort	functional annotation of rare gene aberration drivers of pancreatic cancer
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/ad00a3ec62c944099c564237f8e7c498
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Functional annotation of rare gene aberration drivers of pancreatic cancer

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